Protocol for Exercise Hemodynamic Assessment: Performing an Invasive Cardiopulmonary Exercise Test in Clinical Practice
Year: 2015
Type: review
Abstract: Invasive cardiopulmonary exercise testing (iCPET) combines full central hemodynamic assessment with continuous measurements of pulmonary gas exchange and ventilation to help in understanding the pathophysiology underpinning unexplained exertional intolerance. There is increasing evidence to support the use of iCPET as a key methodology for diagnosing heart failure with preserved ejection fraction and exercise-induced pulmonary hypertension as occult causes of exercise limitation, but there is little information available outlining the methodology to use this diagnostic test in clinical practice. To bridge this knowledge gap, the operational protocol for iCPET at our institution is discussed in detail. In turn, a standardized iCPET protocol may provide a common framework to describe the evolving understanding of mechanism(s) that limit exercise capacity and to facilitate research efforts to define novel treatments in these patients.
Source: Pulmonary Circulation
DOI: 10.1086/683815
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: U.S. Department of Veterans Affairs, Pulmonary Hypertension Association, Brigham and Women's Hospital, Gilead Sciences, Office of Research and Development, Dunlevie Family Fund for Adult Congenital Heart Disease, Cardiovascular Medical Research and Education Fund, Gilead Research Scholars, National Institutes of Health, Clinical Science Research and Development, National Heart, Lung, and Blood Institute
OpenAlex ID: W2233338094