Évaluation de l’équilibre des AVK post-hospitalisation, chez des sujets âgés, traités pour une Fibrillation Atriale : FAREMBOL-AMBU : étude prospective sur un territoire géographique déterminé de la région Aquitaine
Year: 2015
Type: dissertation
Abstract: Introduction: Global time in therapeutic range (TTR), for patients over 75 years old in a specific geographic area of Aquitaine was 58%. The purpose of the prospective real life FAREMBOL AMBU trial, was to assess the impact of several actions on the TTR improving. Methods: Throughout one year, several interventions were launched including oral anticoagulation computer-aided management, communication between health professionals and patient’s information. TTR was computed according to Rosendaal's method. Results: The overall follow-up duration was of 74 patient-years including 210 patients. The time spent between therapeutic range 2 to 3 was 64%. During follow-up 47 adverse events occurred. 5 were bleeding complications (TTR = 34%), 9 were ischemic strokes (TTR = 48%) and 33 were fatal (TTR 57%). The longer the time in therapeutic range, the better the survival (r=0.8593). Conclusion: The study proved that the actions taken have improved oral anticoagulation management. These good management practices should be applied in every hospital and by ambulatory physicians.
Source: HAL
Author: Dorothée Bureau
Institution: Université de Bordeaux
Language: French
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2236985053