Work

Recent Progress on Countercurrent Chromatography Modeling

Year: 2014

Type: article

Abstract: As countercurrent chromatography is becoming an established method in chromatography for many kinds of products, it is becoming increasingly important to model the process and to be able to predict the peaks for a given process. The CCC industries are looking for rapid methods to analyze the processes of countercurrent chromatography and select suitable solvent system. In this paper, recent progress is reviewed in the development and demonstration of several types of models of countercurrent chromatography. Literature lists a number of countercurrent chromatography (CCC) models that can predict the retention time and to a certain extent the peak width of a solute eluting from a CCC column, such as cell model, CCD model, CSTRs model, probabilistic model, temperature dependence plate model, physical models, etc.

Source: Journal of Liquid Chromatography & Related Technologies

DOI: 10.1080/10826076.2014.941268

Authors: Fengkang Wang, Yoichiro Ito, Yun Wei

Institutions: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, National Institutes of Health, National Heart, Lung, and Blood Institute

Language: English

Topic: Chromatography in Natural Products

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institutes of Health

Award: G4705346009