Work

Capparis spinosa reduces Doxorubicin-induced cardio-toxicity in cardiomyoblast cells.

Year: 2016

Type: article

Abstract: OBJECTIVE: against DOX-induced cytotoxicity in H9c2 cells. MATERIALS AND METHODS: extract for 4 hr before DOX treatment in all trials. RESULTS: decreased apoptotic induction significantly, at the doses of 50 µg/ml (p<0.05), 100 µg/ml (p<0.01) and 200 µg/ml (p<0.001). CONCLUSION: could exert cardioprotective effects against DOX-induced toxicity that might be mediated via its antioxidant activity.

Source: PubMed

Authors: Seyed Hadi Mousavi, Azar Hosseini, Elham Bakhtiari, Hassan Rakhshandeh

Institution: Mashhad University of Medical Sciences

Language: English

Topic: Chemotherapy-induced cardiotoxicity and mitigation

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2238115363

FWCI: 1.423

Cites: 27

Cited by: 13

Related to: 10