Mechanism of the antiproliferative action of leflunomide. A77 1726, the active metabolite of leflunomide, does not block T-cell receptor-mediated signal transduction but its antiproliferative effects are antagonized by pyrimidine nucleosides.
Year: 1995
Type: article
Source: PubMed
Authors: W W Cao, P N Kao, A C Chao, P Gardner, J Ng, R E Morris
Institutions: Stanford Medicine, Stanford University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W2242493795