Work

Development and evaluation of agents for targeting visceral amyloid.

Year: 2011

Type: article

Abstract: and can be used to image the deposits. The interaction of this peptide, designated p5, with amyloid is dependent on the net positive charge and truncated forms that would be more desirable as clinical imaging agents were found to be significantly less efficient for amyloid imaging. The development and positive preclinical validation of these two reagents offers potential new therapeutic and diagnostic tools for patients with these devastating diseases.

Source: PubMed

Authors: Jonathan S Wall, Alan Solomon, Stephen J Kennel

Institution: University of Tennessee at Knoxville

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Award: Preclinical Diagnostic Imaging of Amyloid