Get started
Work

Oncolytic poliovirus directs tumor antigen presentation and T cell activation in vitro

Year: 2015
Type: article
Abstract: Meeting abstracts Our group has developed an oncolytic poliovirus, PVSRIPO, capable of lysing malignant cells while generating inflammation at the site of the tumor. PVSRIPO is a recombinant polio:rhinovirus chimera, engineered to eliminate neuropathogenicity, that has cancer tropism due to ectopic
DOI: 10.1186/2051-1426-3-s2-p332
Authors: Michael C Brown, Eda Holl, David Boczkowski, Ross Walton, Darell D Bigner, Matthias Gromeier, Smita K Nair
Institution: Duke University
Language: English
Subfield: Immunology
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2247783150
FWCI: 0.412
Cites:
Cited by: 5
Related to: 10