Work

A panoply of errors: polymerase proofreading domain mutations in cancer

Year: 2016

Type: review

Source: Nature reviews. Cancer

DOI: 10.1038/nrc.2015.12

Authors: Emily Rayner, Inge C. van Gool, Claire Palles, Stephen E. Kearsey, Tjalling Bosse, Ian Tomlinson, David N. Church

Institutions: Centre for Human Genetics, University of Oxford, Leiden University Medical Center

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Wellcome Trust, Cancer Research UK, National Institute for Health and Care Research, Academy of Medical Sciences, Medical Research Council, Biotechnology and Biological Sciences Research Council

Awards: Defects in replicative DNA polymerases linked to cancer predisposition and tumour development, Understanding how ribonucleotide reductase is regulated by the intrinsically disordered protein Spd1, G2854979636, G307466776, G4368767726, G4414390636, G6738805331, Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics., G7632146639

OpenAlex ID: W2252367299

FWCI: 3.955

Cites: 124

Cited by: 377

Related to: 10