The E3 ligase APC/C Cdh1 promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth
Year: 2015
Type: article
Source: Science Signaling
Institutions: Boston University, Beth Israel Deaconess Medical Center, Harvard University, Shanghai University of Traditional Chinese Medicine, Longhua Hospital Shanghai University of Traditional Chinese Medicine, St George's, University of London, The University of Texas at Dallas, University of Alabama at Birmingham, UAB Medicine, University of Pennsylvania, Tufts University, Massachusetts General Hospital, University of Oxford, Ludwig Cancer Research
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
Funders: American Cancer Society, Harry J. Lloyd Charitable Trust, Ludwig Institute for Cancer Research, Wellcome Trust, National Natural Science Foundation of China, National Institutes of Health, National Key Research and Development Program of China, National Cancer Institute, National Institute of General Medical Sciences, Program for Changjiang Scholars and Innovative Research Team in University
Awards: G1129552073, G2029884990, G3190854471, G3204682653, G3716469210, G5553629403, Congenic cell bank for pigmentary mutations, Interplay between Cdh1 and major regulatory pathways in human cancer, G6355270932, A Novel Oncogenic Role for Cdc20 Implications in Adult T Cell Leukemia Treatment, G881274658, G9000241899
OpenAlex ID: W2252947445