Work

Ribosomal RNA gene sequences and hominoid phylogeny.

Year: 1990

Type: article

Abstract: Sequences totaling 3,500 bases from the 28S rRNA gene and from one of the ribosomal internal transcribed spacers (ITS1) have been determined for human, chimpanzee (Pan troglodytes), gorilla (Gorilla gorilla), and orangutan (Pongo pygmaeus). Analyses of the rRNA alignments show (1) a clustering of substitutions in the "variable regions" of the 28S gene, (2) a 1.5-3-fold increase in divergence in the transcribed spacer over that in the exon, and (3) that human and chimpanzee are the most closely related pair, in agreement with the results of Miyamoto et al., Sibley and Ahlquist, and Caccone and Powell.

Source: Molecular Biology and Evolution

DOI: 10.1093/oxfordjournals.molbev.a040600

Authors: I L Gonzalez, J E Sylvester, T F Smith, D Stambolian, R D Schmickel

Institutions: Hahnemann University Hospital, University of Pennsylvania, Harvard University

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G6006636538, ORGANIZATION AND STRUCTURE OF REPEATED HUMAN GENES