The axoneme: the propulsive engine of spermatozoa and cilia and associated ciliopathies leading to infertility
Year: 2016
Type: review
Abstract: Three-dimensional CPMA Central pair microtubule apparatus FS Fibrous sheathThe first investigation of sperm flagellar morphology was begun in 1888, by German cytologist Ballowitz [6], who observed using light microscopy and mordant stains that a Capsule This review article provides a critical analysis of the structure and molecular mechanisms of the microtubule axoneme of cilia and sperm flagella and their associated elements required for male fertility.A broad range of genetic and molecular defects (ciliopathies) are considered in the context of human diseases involving impaired motility in cilia and sperm flagella, providing provocative thought for future research in the area of male infertility.
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,690
Funders: National Science Foundation, Brandeis University, University of Texas Southwestern Medical Center, University of Oxford, Consejo Nacional de Investigaciones Científicas y Técnicas, National Institutes of Health, U.S. Public Health Service, Agencia Nacional de Promoción Científica y Tecnológica, National Institute of General Medical Sciences
OpenAlex ID: W2258022996