Feasibility of non-invasive optical blood-glucose detection using overtone circular dichroism
Year: 2016
Type: preprint
Abstract: Diabetes is one of the most debilitating and costly diseases currently plaguing humanity. It is a leading cause of death and dismemberment in the world, and we know how to treat it. Accurate, continuous monitoring and control of blood glucose levels via insulin treatments are widely known to mitigate the majority of detrimental effects caused by the disease. The primary limitation of continuous glucose monitoring is patient non-compliance due to the unpleasant nature of "finger-stick" testing methods. This limitation can be largely, or even completely, removed by non-invasive testing methods. In this report, we demonstrate the vibrational overtone circular dichroism properties of glucose and analyze its use as a method of non-invasive glucose monitoring, capable of assuaging this trillion dollar scourge.
Source: arXiv (Cornell University)
Institutions: Engility (United States), Texas A&M University
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: green
Awards: G1527163402, Collaborative Research in Biophotonics: Towards high-resolution, label-free molecular imaging in deep tissue via stimulated Raman excitation and ultrasound detection, G3099161694, MRI: Development of a microfluidic flow cytometer for high-throughput noninvasive single-cell physio-chemical analysis, Shedding new light on cell-matrix interactions: instrumentation development for non-invasive, real-time microscopic elasticity imaging, Facilitating remote chemical sensing with random Raman lasing
OpenAlex ID: W2259500616