Investigation on Phagocytosis Index & Humoral Immunity in Patients of Type 1Diabetes in Thi-Qar Province
Year: 2016
Type: article
Study design: Observational Study
Abstract: The current study was conducted at the Center for Diabetes and Endocrinology of the Health Directorate in Thi-Qar province, during the period from October 2013 to May 2014.The study aimed and evaluate immune status of diabetes type I patients by measuring the levels of immunoglobulins ( IgM, IgG, IgA ) by single redial immune diffusion (SRID) and the study included test phagocytic cells on phagocytosis (coefficient of phagocytosis) and measurement hematological parameters(red blood cells count , hemoglobin, packed cell volume and count the total and differential white blood cells) .The study included a total of 100 patients with type I diabetes (51 males) and (49 females) and there aged between 1-40 years.Levels were measured in serum immunoglobulins for 20 a sample of patients with type I diabetes, also examined the levels of immunoglobulins in the serum of 10 samples from healthy people in the control group.The results of the statistical analysis showed high significant increase (P ≤ 0.001) in the immunoglobulins in serum IgM,, IgG IgA in patients with type I diabetes compared with healthy control group .Decrease coefficient phagocytosis was significantly (P ≤ 0.001) in all patients with diabetes mellitus type I compared a group of control, either with respect to the hematological parameters have explained the results of the current study, the lack of significant differences( P ≤ 0.05) in the rates of the values of the RBCs and Hb and PCV in all patients diabetes type I, compared with the control group, also increased the rate of counting the total of WBCs and count differential cell lymphocytes, eosinophil , basophil, and monocyte (P ≤ 0.001) in patients with diabetes mellitus type I compared with healthy people in the control group .
Authors: Ali Naeem Salman, Maytham Talib Qasim
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2259815736