Work

A Multiligand Based Pd Catalyst for C−N Cross-Coupling Reactions

Year: 2010

Type: article

Abstract: An alternative approach to catalyst development, which led to a Pd catalyst based on two biarylphosphine ligands for C-N cross-coupling reactions, is reported. By effectively being able to take the form of multiple catalysts this system manifests the best properties that catalysts based on either of the two ligands exhibit separately and displays the highest reactivity and substrate scope of any system that has been reported to date for these reactions.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja108074t

Authors: Brett P. Fors, Stephen L. Buchwald

Institution: Massachusetts Institute of Technology

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: CATALYTIC METHODS FOR ORGANIC SYNTHESIS, Late Transition Metal Catalysts for Organic Synthesis