Cardiac biomarkers: a focus on cardiac regeneration.
Year: 2011
Type: article
Abstract: HISTORICALLY, BIOMARKERS HAVE BEEN USED IN TWO MAJOR WAYS TO MAINTAIN AND IMPROVE BETTER HEALTH STATUS: first, for diagnostic purposes, and second, as specific targets to treat various diseases. A new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born. In this approach, scientists are successfully taking human skin cells (previously considered terminally-differentiated cells) and re-programming them into functional cardiac myocytes and other cell types in vitro. A cell reprograming approach for treatment of cardiovascular diseases will revolutionize the field of medicine and significantly expand the human lifetime. Availability of a comprehensive catalogue for cardiac biomarkers is necessary for developing cell reprograming modalities to treat cardiac diseases, as well as for determining the progress of reprogrammed cells as they become cardiac cells. In this review, we present a comprehensive survey of the cardiac biomarkers currently known.
Source: PubMed
Authors: Reza Forough, Catherine Scarcello, Matthew Perkins
Institutions: Bellevue College, Bellevue University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2263333856