Pharmacokinetics of antiretroviral drugs in infancy : clinical
Year: 2009
Type: article
Abstract: Dosing in infancy is complicated by inadequate characterisation of pharmacokinetics, unpredictable drug concentrations and a lack of suitable dosage forms. Additional challenges are presented by the concomitant administration of interacting drugs (e.g. rifampicin in antituberculosis treatment) and disease conditions that may alter drug disposition. The extent and implications of breastmilk transfer of drugs to the infant are poorly understood. New technologies facilitate pharmacokinetic studies in infants and will improve access to therapeutic drug monitoring.
Authors: Helen McIlleron, Hermien Gous
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $605
OpenAlex ID: W2263372409