Work

Mood Differences Among Parkinson’s Disease Patients With Mild Cognitive Impairment

Year: 2016

Type: article

Abstract: Studies with healthy elderly adults suggest that apathy, depression, and anxiety are more common among individuals with mild cognitive impairment (MCI). This study examined differences in mood/amotivational symptoms among patients with Parkinson's disease (PD) with and without MCI. Patients with PD (N=214) underwent neurocognitive evaluations including assessment of apathy (Apathy Scale), depression (Beck Depression Inventory-II), and trait anxiety (State-Trait Anxiety Inventory trait scale). Trait anxiety and depression were more severe in patients with PD with MCI. Delineation of MCI into amnestic and nonamnestic subtypes revealed greater depression, apathy, and anxiety among patients with PD with amnestic MCI relative to cognitively intact patients with PD. Patients with PD and MCI report greater mood symptoms compared to patients with PD who are cognitively intact.

Source: Journal of Neuropsychiatry

DOI: 10.1176/appi.neuropsych.15090221

Authors: Jacob D. Jones, Paul Mangal, Jacob Lafo, Michael S. Okun, Dawn Bowers

Institutions: University of Florida Health, University of Florida

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute of Mental Health, National Institute of Nursing Research, National Institute of Neurological Disorders and Stroke