Work

Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors

Year: 2015

Type: article

Abstract: (13)C-pyruvate hyperpolarized magnetic resonance imaging (HP-MRI) is emerging as a viable quantitative biomarker for solid tumor response and normal tissue toxicity after radiotherapy. This technology effectively predicts response related to metabolic agents or alterations in the tumor microenvironment, but challenges remain to be addressed to ensure successful translational implementation. See related article by Saito et al., p. 5073.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-15-1214

Authors: Stephen Y. Lai, C. David Fuller, Pratip K. Bhattacharya, Steven J. Frank

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute