Work

Ultrasound-driven Megahertz Faraday Waves for Generation of Monodisperse Micro Droplets and Applications

Year: 2015

Type: article

Abstract: Our theoretical findings on instability of Faraday waves at megahertz (MHz) drive frequency and realization of silicon-based MHz multiple-Fourier horn ultrasonic nozzles (MFHUNs) together have enabled generation of mono-disperse droplets of controllable diameter (2.5-6.0 μm) at very low electrical drive power (<0.5 Watt). The resulting battery-run clogging-free droplet generator has imminent application to pulmonary (inhalation) drug delivery and other potential applications. Here an update of advances on analysis and design of the MHz MFHUNs and the underlying physical mechanism for generation of mono-disperse micro droplets, and the nebulizer platform for application to detoxification of cyanide poisoning are presented.

Source: Physics Procedia

DOI: 10.1016/j.phpro.2015.08.179

Authors: Chen S. Tsai, Rong W. Mao, Shih K. Lin, Shirley C. Tsai, Gerry Boss, Matt Brenner, Gerry Smaldone, Sari Mahon, Kaveh Shahverdi, Yun Zhu

Institutions: University of California, Irvine, Beckman Laser Institute and Medical Clinic, State University of New York, Stony Brook University Hospital, Stony Brook Medicine, Stony Brook University

Language: English

Topic: Electrohydrodynamics and Fluid Dynamics

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: diamond

Funder: National Institutes of Health

OpenAlex ID: W2266770997

FWCI: 0.15

Cites: 15

Cited by: 6

Related to: 10