Towards dial-a-molecule by integrating continuous flow, analytics and self-optimisation
Year: 2016
Type: review
Abstract: The employment of continuous-flow platforms for synthetic chemistry is becoming increasingly popular in research and industrial environments. Integrating analytics in-line enables obtaining a large amount of information in real-time about the reaction progress, catalytic activity and stability, etc. Furthermore, it is possible to influence the reaction progress and selectivity via manual or automated feedback optimisation, thus constituting a dial-a-molecule approach employing digital synthesis. This contribution gives an overview of the most significant contributions in the field to date.
Source: Chemical Society Reviews
DOI: 10.1039/c5cs00793c
Authors: Victor Sans, Leroy Cronin
Institutions: University of Nottingham, University of Glasgow
Language: English
Subfield: Fluid Flow and Transfer Processes
Field: Chemical Engineering
Domain: Physical Sciences
Open Access status: green
Awards: International Collaboration in Chemistry - Modular microtubular architectures for photo-driven water splitting, Plug'n Play Photosynthesis for Rubisco Independent Fuels, Energy and the Physical Sciences: Hydrogen Production using a Proton Electron Buffer, EPSRC Centre for Innovative Manufacturing for Continuous Manufacturing and Crystallisation, The EmergeNET: Towards a Unifying Investigation in Emergence, Emergent Phenomena and Complexity, Molecular-Metal-Oxide-nanoelectronicS (M-MOS): Achieving the Molecular Limit, A Digital DNA Nano Writer (DNA NanoFab), Synthetic Biology applications to Water Supply and Remediation, Programmable Molecular Metal Oxides (PMMOs): From Fundamentals to Application, 14-PSIL: Plug and Play Photosynthesis for RuBisCO Independent Fuels, Programmable 'Digital' Synthesis for Discovery & Scale-up of Molecules, Clusters & Nanomaterials, The Multicorder
OpenAlex ID: W2268401673