The effect of 2% salicylic acid as a support of 10% benzoil peroxide gel for mild to moderate acne vulgaris.
Year: 2015
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: ABSTRACT\nRahajeng Musy, Kristiana Etnawati, Suyoto The effect of 2% salicylic acid as a support of 10% benzoil peroxide gel for mild to moderate acne vulgaris.\nBackground: Cleansing is necessary before the application of topical therapy for acne vulgaris. However ordinary soap leads to dryness. Two percent salicylic acid has comedolytic, anti inflammation and moisturizing activity.\nObjective: The aim of this study was to assess the effectiveness of 2% salicylic acid soap as a support of 10% benzoil peroxide gel for mild to moderate acne vulgaris.\nMaterial and method: The design of this study was randomized, double blind, clinical trial. Fifty two\nfemales with mild to moderate acne vulgaris with the mean of the age was 18.9 ± 3.06 years old were divided into 2 groups. The first group was treated with 2% salicylic acid soap and the second group was treated with soap base, in addition to 10% benzoil peroxide gel for both groups. The clinical assessment was conducted by counting the acne lesion at 2, 4, 8, and 12 week. While the level of moisture and sebum of the skin was measured by corneometer and sebumeter of Courage – Khazaka at 4, 8, and 12 week. The difference between 2 groups was analyzed statistically by t-test, chi-square test and Mann-Whitney U test. The difference was considered to be significant if p < 0.05.\nResult: There was significant reduction of the open comedone in salicylic acid soap group (p
Author: Rahajeng Musy Rahajeng Musy
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $50
OpenAlex ID: W2271342361