Work

Relative contractile motion of the rings in a switchable palindromic [3]rotaxane in aqueous solution driven by radical-pairing interactions

Year: 2014

Type: article

Abstract: Artificial muscles are an essential component for the development of next-generation prosthetic devices, minimally invasive surgical tools, and robotics. This communication describes the design, synthesis, and characterisation of a mechanically interlocked molecule (MIM), capable of switchable and reversible linear molecular motion in aqueous solution that mimics muscular contraction and extension. Compatibility with aqueous solution was achieved in the doubly bistable palindromic [3]rotaxane design by using radical-based molecular recognition as the driving force to induce switching.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c4ob01228c

Authors: Leah S. Witus, Karel J. Hartlieb, Yuping Wang, Aleksandrs Prokofjevs, Marco Frasconi, Jonathan C. Barnes, Edward J. Dale, Albert C. Fahrenbach, J. Fraser Stoddart

Institutions: Northwestern University, Massachusetts Institute of Technology, Tokyo Institute of Technology, Howard Hughes Medical Institute, Massachusetts General Hospital, Earth-Life Science Institute, Center for Computational and Integrative Biology, Massachusetts General Hospital

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: National Science Foundation, U.S. Department of Defense, Howard Hughes Medical Institute, Northwestern University, King Abdulaziz City for Science and Technology, National Institutes of Health, National Defense Science and Engineering Graduate, International Institute for Nanotechnology, Northwestern University, National Institute of General Medical Sciences

Awards: Architectures for the macromolecule-mediated assembly of palindromic rotaxanes, G8239090096

OpenAlex ID: W2100898510

FWCI: 2.055

Cites: 64

Cited by: 30

Related to: 10