Year: 2013
Type: article
Study design: Observational Study
Abstract: Background: Disability is the most important determinants of disease course, treatment \n \nand rehabilitation outcomes and consequently the quality of life in patients with multiple \n \nsclerosis. The aim of the present study was to determine the relationship of disability and \n \nquality of life in multiple sclerosis patients. \n \n \n \nMethods: This cross-sectional study was performed on 325 patients referred to the physiotherapy unit of the Multiple Sclerosis Society of Iran (Tehran). Data collection tools were MSQOL-54 questionnaire for evaluating quality of life and Expanded Disability Status \n \nScale (EDSS) for assessing the degree of disability. Data analysis was performed through \n \nSPSS16 and using t-test, chi-square test and linear regression. \n \nResults: Mean age of patients was 39.1± 10.4 years. Among 14 domains of quality of life, \n \nthe highest score was related to pain (67.8 ± 25.7) and the least was related to role limitations \n \ndue to physical problems (31 ± 17.1). Linear regression model showed significant \n \nnegative effect of disability on both physical and mental health domains of quality of life \n \n(P <0.001). \n \n \n \nConclusion: The present study showed the association between disability and factors such \n \nas age of disease onset and gender and quality of life in multiple sclerosis patients. Therefore \n \nsupportive care to reduce disability and maintain patients’ functions at the highest \n \npossible level, particularly in women and patients with later age of disease onset, in order \n \nto improve the quality of life is recommended. \n \n \n \nKeywords: Disability, Quality of life, Multiple sclerosis, MSQOL-54
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2272531786