Year: 2014
Type: dissertation
Abstract: __Abstract__ \n \nAortic disease represents one of the major causes of morbidity and mortality in the \nindustrialized society. Approximately 2% of all deaths are caused by aortic aneurysm and \ndissections [1]. Aneurysms are defined as a local widening of the artery with more than \n50 percent of the normal diameter [2]. An aneurysm can result in a fatal aortic rupture or \nin an aortic dissection, which is a tear in the wall of the artery that causes blood to flow \nbetween the layers of the wall and forces the layers apart [3]. Dissections involving the \nascending aorta, Stanford type A dissections, have a mortality rate of 1-2% per hour and \nshould be immediately treated surgically [4], while dissections occurring in the descending \naorta are usually treated medically and have an in-hospital mortality of about 10% [5]. \nHowever, an acute aortic dissecti
Author: Natasja W. M. Ramnath
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Funder: European Commission
OpenAlex ID: W2273151965