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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

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Year: 2015
Type: article
Source: Nature Chemical Biology
DOI: 10.1038/nchembio.1984
Authors: Luc de Waal, Timothy A Lewis, Matthew G Rees, Aviad Tsherniak, Xiaoyun Wu, Peter S Choi, Lara Gechijian, Christina Hartigan, Patrick W Faloon, Mark J Hickey, Nicola Tolliday, Steven A Carr, Paul A Clemons, Benito Munoz, Bridget K Wagner, Alykhan F Shamji, Angela N Koehler, Monica Schenone, Alex B Burgin, Stuart L Schreiber, Heidi Greulich, Matthew Meyerson
Institutions: Broad Institute, Dana-Farber Cancer Institute, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, Harvard University
Language: English

Topic: Phosphodiesterase function and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, National Human Genome Research Institute, National Cancer Institute
Awards: G2010999335, G374291444, G4376379040, Cancer dependencies associated with genomic alterations and targeted by small mol, G5171651879, Cancer Center Support (Core) Grant
OpenAlex ID: W2273218209
FWCI: 2.572
Cites: 52
Cited by: 94
Related to: 10
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