Work

Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR

Year: 2016

Type: article

Source: Nature Neuroscience

DOI: 10.1038/nn.4235

Authors: Derek J C Tai, Ashok Ragavendran, Poornima Manavalan, Alexei Stortchevoi, Catarina M Seabra, Serkan Erdin, Ryan L Collins, Ian Blumenthal, Xiaoli Chen, Yiping Shen, Mustafa Sahin, Chengsheng Zhang, Charles Lee, James F Gusella, Michael E Talkowski

Institutions: Harvard University, Massachusetts General Hospital, Universidade do Porto, Instituto de Ciências Biomédicas Albel Salazar, Capital Institute of Pediatrics, Boston Children's Hospital, The Jackson Laboratory for Genomic Medicine, Ewha Womans University, Broad Institute

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Mental Health, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1126345087, G119017098, An Integrative Analysis of Structural Variation for the 1000 Genomes Project, G2330089102, G278894908, G5827989630, Dissecting recurrent microdeletion syndromes using dual-guide genome editing, Complex Genetic Architecture of Chromosomal Aberrations in Autism, G8282690708, Complex Genetic Architecture of Chromosomal Aberrations in Autism

OpenAlex ID: W2273569821

FWCI: 3.008

Cites: 44

Cited by: 91

Related to: 10