Are routine testosterone assays good enough?
Year: 2005
Type: article
Abstract: Burgeoning clinical demand has driven the automation of testosterone measurement. Original assays were onerous and labour intensive and involved extraction and chromatography steps followed by RIA. As more specific antibodies were developed, kits were manufactured that dispensed with first chromatography and then extraction; so-called “direct” assays. Today most routine testosterone measurements are performed using direct automated chemiluminescent methods run on multipurpose immunoassay analysers. Analysis has become cheap, convenient, and rapid and as a result easily available, to match the very high clinical demand. In our laboratory for example, requests for testosterone increased by 2.7 times over 3 years (1999 to 2002) and have stabilised at this level since then.
Source: Europe PMC (PubMed Central)
Author: Sydney S Sacks
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2275084017