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Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study

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Year: 2015
Type: article
Study design: Clinical Trial
Source: Cancer Chemotherapy and Pharmacology
DOI: 10.1007/s00280-015-2882-9
Authors: Anthony W. Tolcher, Patricia LoRusso, Jennifer Arzt, Todd A. Busman, Guinan Lian, Niki S. Rudersdorf, Carol Ann Vanderwal, Jeffrey F. Waring, Jianning Yang, Kyle D. Holen, Lee S. Rosen
Institutions: South Texas Accelerated Research Therapeutics, Yale Cancer Center, Yale University, AbbVie (United States), University of California, Los Angeles
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: AbbVie, Genentech
OpenAlex ID: W2277993502
FWCI: 1.419
Cites: 23
Cited by: 40
Related to: 10
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