Work

Regulation of Calcium Signaling by Primary Cilia and Its Role in Polycystic Kidney Disease Pathogenesis

Year: 2014

Type: article

Abstract: Primary cilia with a diameter of ~200 nm have been implicated in development and disease.Calcium signaling within a primary cilium has never been directly visualized and has therefore remained a speculation.Fluid-shear stress and dopamine receptor type-5 (DR5) agonist are among the few stimuli that require cilia for intracellular calcium

Source: OhioLink ETD Center (Ohio Library and Information Network)

Author: Xingjian Jin

Institution: University of Toledo

Language: English

Topic: Genetic and Kidney Cyst Diseases

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2279541557

FWCI:

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Related to: 10