Work

Sub-diffuse optical biomarkers characterize localized microstructure and function of cortex and malignant tumor

Year: 2016

Type: article

Abstract: ), error 10%], blood volume fraction [(1-3 vol%), error 7%], and a dimensionless metric of anisotropic scattering, γ, that is sensitive to submillimeter tissue ultrastructure [(1.29-2.06), error 11%]. In vivo sub-diffusive optical data acquired during clinical neurosurgeries characterize differences in microstructure (γ), perfusion (blood volume), and metabolism (PpIX fluorescence) between normal cortex and malignant tumor.

Source: Optics Letters

DOI: 10.1364/ol.41.000781

Authors: Jaime J. Bravo, Keith D. Paulsen, David W. Roberts, Stephen C. Kanick

Institutions: Dartmouth College, Dartmouth–Hitchcock Medical Center, Dartmouth Cancer Center

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Neurological Disorders and Stroke