Peroxisomal proliferator activated receptor-gamma-co-activator-1alpha promoter methylation in blood from children at 5–7 years predicts their adiposity from 9 to 14 years
Year: 2013
Type: article
Study design: Observational Study
Abstract: We have investigated the effect of increasing age in childhood on the methylation of specific CpG loci in the peroxisomal proliferator-gamma-co-activator-(PGC)-1α promoter that have been shown previously to be related to its transcriptional activity in adults (3). We then determined whether loci that exhibited temporal stability predicted adiposity.
Source: Figshare
Authors: Clarke-Harris, Rebecca, Hosking, Joanne, J. Wilkin, Terence, Pinkney, Jonathan, Jeffery, Alison, S. Metcalf, Brad, M. Godfrey, Keith, Voss, Linda, Karen Lillycrop, Burdge, Graham, Price, Leonie
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6977422743