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A bioinformatics characterization of the RNA-dependent RNA polymerase from the parasitic fungi, Metarhizium anisopliae.

Year: 2014

Type: article

Abstract: Metarhizium anisopliae is an entomopathogenic organism that is parasitic towards insects, including those that serve as vectors for human disease, including malaria parasite infected Anopheles mosquitoes. Directed bioengineering of parasitic M. anisopliae has been proposed as a potentially novel vector control strategy. However, many parasitic fungi posses a RNA-dependent RNA polymerase (RdRp) gene that serves as a defence against transgenes. Here we characterize the RdRp gene of M. anisopliae, including the context of the gene in relation to surrounding genes and theoretical modeling based on the RdRp enzyme of Neurospora crassa.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

Authors: C. N. Weir, Emily Wong, Glenn F. King

Institutions: The University of Melbourne, Walter and Eliza Hall Institute of Medical Research, European Bioinformatics Institute, Wellcome Trust, The University of Queensland, Institute for Molecular Bioscience

Language: English

Topic: Entomopathogenic Microorganisms in Pest Control

Subfield: Insect Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2282314272

FWCI:

Cites: 14

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Related to: 10