Work

DNA Methylation Analysis in Human Cancer

Year: 2012

Type: book-chapter

Abstract: The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

Source: Methods in molecular biology

DOI: 10.1007/978-1-62703-287-2_7

Authors: Eileen O’Sullivan, Michael Goggins

Institutions: Johns Hopkins University, Johns Hopkins Medicine, Johns Hopkins Hospital

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Awards: G1575986659, Markers of Early Pancreatic Cancer, Predicting pancreatic cancer responses for a Parp inhibitor-based clinical trial, SPORE in Gastrointestinal Cancers, G970037175