Year: 2009
Type: article
Abstract: outside source for gamma radiation.The samples were returned back in order to study the effect of gamma radiation on the NO release as well as the stability.Similarly, a transdermal multilayered patch was designed using ion exchange resin bound H + , NO - 2 and ASC -ions encapsulated in a polyurethane matrix, which also delivered NO.In another experiment, a transdermal patch was developed using polyethyleneimine (PEI) and polyethyleneimine-Cellulose (PEI-Cellulose).PEI and PEI-Cellulose were modified with NO under pressure and electrospun with the polyurethane polymer.For all of the above combinations, release profiles for NO were studied and stability studies were carried out.In addition to a multilayered patch, a topical cream was developed using Pluronic ® , ion exchange bound nitrite ions, MCC stabilized ascorbic acid, and salicylic acid.The cream can be applied topically for the site specific delivery of NO.The results show stable, sustained and site specific delivery of NO. v ACKNOWLEDGEMENT I am most thankful to Dr. Daniel Smith, my advisor, for all his support.He is full of innovative ideas and he guided me throughout the ups and downs of my research work.During my graduate studies I learned a lot from him.He is always inspirational to me.Also I am
Author: Mahesh Bhide
Institution: University of Akron
Language: English
Topic: Wound Healing and Treatments
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2282549147