The Effect of Preoperative Ibuprofen and Acetaminophen on the Efficacy of the Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis
Year: 2010
Type: article
Abstract: Previous studies (12,13) have suggested that preoperative medication may increase the success rate of the IAN block.Modaresi et al. (12) compared acetaminophen with codeine, ibuprofen, and a placebo in 60 patients with irreversible pulpitis.Each drug was administered one hour before anesthesia delivery.Using lower tooth sensitivity levels (TSLs) to measure effectiveness, the authors found significantly lower TSLs in both medication groups compared with the placebo medication.The ibuprofen group also had significantly lower TSLs when compared to the acetaminophen with codeine group.However, the authors did not perform endodontic accesses to confirm anesthetic effectiveness.Ianiro et al. (13) compared acetaminophen, a combination of acetaminophen and ibuprofen, and a placebo in 40 patients with irreversible pulpitis.The medications were administered 30 minutes before giving anesthesia.If the patient had no pain to cold (Green Endo-Ice ® ) or no pain on endodontic access, the inferior alveolar nerve block was considered successful.The authors found a 71% success rate for the acetaminophen group, a 76% success rate for the combination of acetaminophen and ibuprofen, and a 46% success rate for the placebo group.While the authors stated that there was a trend toward higher success in the medication groups, they found no significant differences among the groups.Recent clinical studies (14, 15) found that giving only ibuprofen preoperatively did not significantly improve the success rate of the IAN block in patients with irreversible pulpitis.Aggarwal et al. ( 14) compared the effect of oral premedication with ibuprofen, ketorolac, or a placebo on the anesthetic efficacy of the IAN block.Three groups of 24 patients each were given either 600 mg of ibuprofen, 20 mg of ketorolac, or
Author: Michael G. Simpson
Institution: The Ohio State University
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2284741191