Probiotics in prevention and treatment of obesity: a critical view
Year: 2016
Type: review
Abstract: The worldwide prevalence of obesity more than doubled between 1980 and 2014. The obesity pandemic is tightly linked to an increase in energy availability, sedentariness and greater control of ambient temperature that have paralleled the socioeconomic development of the past decades. The most frequent cause which leads to the obesity development is a dysbalance between energy intake and energy expenditure. The gut microbiota as an environmental factor which influence whole-body metabolism by affecting energy balance but also inflammation and gut barrier function, integrate peripheral and central food intake regulatory signals and thereby increase body weight. Probiotics have physiologic functions that contribute to the health of gut microbiota, can affect food intake and appetite, body weight and composition and metabolic functions through gastrointestinal pathways and modulation of the gut bacterial community.
Source: Nutrition & Metabolism
Institutions: Università Cattolica del Sacro Cuore, The University of Texas at Austin, Slovak Academy of Sciences, Institute of Geotechnics of the Slovak Academy of Sciences, University Hospital Bratislava, Comenius University Bratislava, University of Pardubice, Hospital Universitario Central de Asturias, University of Veterinary Sciences Brno, Masaryk University
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,590
OpenAlex ID: W2285227042