Predictors of Responsiveness to Vitamin D Supplementation and Outcomes Assessment in Patients Undergoing Roux-en-Y Gastric Bypass Surgery
Year: 2014
Type: dissertation
Study design: Observational Study
Abstract: Background: Vitamin D is one of the most common micronutrient deficiencies in the obese population awaiting Roux-en-Y gastric bypass (RYGB) surgery and often persists post-operatively despite routinely recommended supplementation, suggesting there may be variable response to this supplementation.However, there are no established indicators that allow clinicians to identify the non-responders, and factors contributing to poor vitamin D repletion after surgery remain unclear.In addition, a patient's nutritional status is an important factor in postoperative morbidity and mortality after any major surgery, but it is unknown how vitamin D status impacts patient outcomes after bariatric procedures.The aims of this study were to identify the predictors of responsiveness to vitamin D supplementation in recipients of RYGB surgery, and to compare patient outcomes as measured by hospital readmissions and emergency room (ER) visits, between responders and non-responders in the year following surgery. Methods:The medical records of patients who underwent RYGB at the University of Washington Medical Center from 2009-2011 and had insufficient vitamin D concentrations (<30 ng/mL) at baseline were reviewed.Non-responders were defined as those who maintained serum 25(OH)D concentrations <30 ng/mL after 1 year; responders were those whose concentrations increased to ≥30 ng/mL after 1 year.Demographic, anthropometric
Author: Jessica Kim
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2285401368