Nuclear factor k B is activated in myelodysplastic bone marrow cells.
Year: 2002
Type: article
Abstract: We describe a significant increase in the DNA binding activity of nuclear factor-kappa B (NF kappa B) in bone marrow cells from patients with myelodysplastic syndrome (MDS) compared with normal donor cells. Furthermore, MDS samples with increased NFkappaB activity consistently showed higher mRNA levels of NFkappaB-regulated cytokines.
Source: PubMed
Authors: Cristina Sanz, Carlos Richard, Felipe Prosper, Jos Luis Fernandez-Luna
Language: English
Topic: NF-κB Signaling Pathways
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2285540945