Work

Biomarkers in psoriatic arthritis: a systematic literature review

Year: 2016

Type: review

Abstract: Psoriatic arthritis (PsA) is characterized by chronic inflammation of peripheral joints and axial skeleton, associated with a strong genetic background. Clinics include enthesitis or dactylitis and extra-articular involvement as uveitis or inflammatory bowel disease, while treatment options range from nonsteroidal anti-inflammatory drugs (NSAIDs) to biologics, targeting TNF α or Th17. No serum autoantibody is associated with PsA, while other biomarkers have been proposed for early diagnosis or to predict treatment response. To better discuss this area of growing interest we performed a systematic review of the literature on biomarkers in PsA. Our research retrieved 408 papers, and 38 were included in the analysis. Based on the available literature, we draw some recommendations for the use of biomarkers in the management of patients with PsA.

Source: Expert Review of Clinical Immunology

DOI: 10.1586/1744666x.2016.1147954

Authors: Elena Generali, Carlo A. Scirè, Ennio G. Favalli, Carlo Selmi

Institutions: Humanitas University, IRCCS Humanitas Research Hospital, Società Italiana di Reumatologia, Istituto Ortopedico Gaetano Pini, University of Milan

Language: English

Topic: Spondyloarthritis Studies and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2285868925

FWCI: 0.794

Cites: 92

Cited by: 56

Related to: 10