Work

Carbapenem- and Colistin-Resistant Enterobacter cloacae from Delta, Colorado, in 2015

Year: 2016

Type: article

Abstract: Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrug-resistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.03055-15

Authors: Andrew P. Norgan, Jarred M. Freese, Patricia M. Tuin, Scott A. Cunningham, Patricio R. Jeraldo, Robin Patel

Institutions: University of Minnesota Rochester, Mayo Clinic

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2286264987

FWCI: 2.927

Cites: 44

Cited by: 41

Related to: 10