Work

A fluorescent surrogate of thymidine in duplex DNA

Year: 2016

Type: article

Abstract: is a new fluorescent thymidine mimic composed of 2'-deoxyuridine fused to dimethylaniline. exhibits the same pKa and base pairing characteristics as native thymidine residues, and its fluorescence properties are highly sensitive to nucleobase ionization, base pairing and metal binding.

Source: Chemical Communications

DOI: 10.1039/c5cc09552b

Authors: Guillaume Mata, Olivia P. Schmidt, Nathan W. Luedtke

Institution: University of Zurich

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W2287980474

FWCI: 3.81

Cites: 54

Cited by: 41

Related to: 10