Work

Survival Prediction Based on Inherited Gene Variation Analysis

Year: 2013

Type: book-chapter

Abstract: There is a significant variation of outcome among ovarian cases. Clinical features such as age, stage, comorbidities, or degree of debulking are known prognostic factors for the disease. However, additional variation remains unexplained, some of which may be due to inherited factors. Here, we describe identification of survival-associated inherited variants in ovarian cancer that can enhance our current prognostic capabilities.

Source: Methods in molecular biology

DOI: 10.1007/978-1-62703-547-7_5

Authors: Mine S. Cicek, Matthew J. Maurer, Ellen L. Goode

Institution: Mayo Clinic

Language: English

Topic: BRCA gene mutations in cancer

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Fred C. and Katherine B. Andersen Foundation, National Cancer Institute