Associação entre tireoidite de Hashimoto e as várias formas de apresentação do carcinoma bem diferenciado da tireoide
Year: 2013
Type: article
Study design: Observational Study
Abstract: Introduction: The association between Hashimoto’s thyroiditis (HT) and well differentiated thyroid carcinoma (DTC) has been discussed in the literature since 1955, when Dailey at al. demonstrated a possible relationship between the two pathologies. Malignant tumors of the thyroid gland represent over 90% of endocrine cancers and have its risk factors have not yet been precisely defined. HT is a major cause of hypothyroidism in places with no iodine deficiency. This disorder is associated with primary lymphoma of the thyroid and can determine molecular alterations that are also present in varying degrees in thyroid carcinoma. objective: This study aimed to evaluate the association between Hashimoto’s thyroiditis and the different forms of presentation of well differentiated thyroid carcinoma. method: We have studied 370 patients who underwent total thyroidectomy for well differentiated thyroid carcinoma between the years of 2000 and 2008. We have analyzed different forms of presentation of well differentiated carcinoma and its relation to the presence or absence of Hashimoto’s thyroiditis, based on pathology. Results: The study showed an association between HT and classic papillary carcinoma of 31.6%, with micropapillary this ratio was 52.8% and the multicentric variant reached 70.3% with p <0.0001 - chi-square test. Follicular carcinoma is associated with the absence of HT
Language: Portuguese
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2288505601