President's address. Common mechanisms of multiple diseases: why vegetables and exercise are good for you.
Year: 2010
Type: article
Abstract: Lifestyle Choices as the Fundamental Platform for Health
A “good diet” and exercise have been recognized to promote health for hundreds and perhaps thousands of years. Epidemiologic studies in the mid 1900s focused initially on cardiovascular disease. Diets high in saturated animal fats resulted in higher cardiovascular mortality rates than did diets that were based on monounsaturated fats such as olive oil, fish and a variety of fruits and vegetables. Similarly, regular exercise gave protection from cardiac events relative to those with sedentary life styles. Dietary studies with and without concomitant assessment of exercise recently revealed salutary benefits of both exercise and diet on a broad range of clinical phenotypes. These findings inferred that at some early stage(s) of many diseases, common pathophysiologic mechanisms were at work. Insights into underlying cellular mechanisms are leading to a transformation in the way we view chronic diseases.
Source: PubMed Central
Author: R Wayne Alexander
Institution: Emory University
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2290172005