High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
Year: 2015
Type: article
Study design: Observational Study
Source: Nature Genetics
DOI: 10.1038/ng.3176
Authors: Philippe Goyette, Gabrielle Boucher, Dermot Mallon, Eva Ellinghaus, Luke Jostins, Hailiang Huang, Stephan Ripke, Elena S Gusareva, Vito Annese, Stephen L Hauser, Jorge R Oksenberg, Ingo Thomsen, Stephen Leslie, Mark J Daly, Kristel Van Steen, Richard H Duerr, Jeffrey C Barrett, Dermot P B McGovern, L Philip Schumm, James A Traherne, Mary N Carrington, Vasilis Kosmoliaptsis, Tom H Karlsen, Andre Franke, John D Rioux
Institutions: Montreal Heart Institute, University of Cambridge, National Institute for Health and Care Research, NIHR Cambridge Biomedical Research Centre, Christian-Albrechts-Universität zu Kiel, Centre for Human Genetics, University of Oxford, Broad Institute, Harvard University, Massachusetts General Hospital, University of Liège, Casa Sollievo della Sofferenza, Azienda Ospedaliero-Universitaria Careggi, University of California, San Francisco, The University of Melbourne, Murdoch Children's Research Institute, University of Pittsburgh, Wellcome Sanger Institute, Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, University of Chicago, Ragon Institute of MGH, MIT and Harvard, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. (United States), Massachusetts Institute of Technology, Oslo University Hospital, University of Oslo, Université de Montréal
Language: English
Topic: Inflammatory Bowel Disease
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
Funders: U.S. Department of Health and Human Services, Leona M. and Harry B. Helmsley Charitable Trust, University of Pittsburgh, Wellcome Trust, Frederick National Laboratory for Cancer Research, National Institute for Health and Care Research, Multiple Sclerosis Society, Academy of Medical Sciences, European Commission, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Crohn's and Colitis UK, Institut National Du Cancer, Exzellenzclusters Entzündungsforschung, National Institutes of Health, Agency for Healthcare Research and Quality, Seventh Framework Programme, Medical Research Council, National Health and Medical Research Council, NIHR Cambridge Biomedical Research Centre, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Dental and Craniofacial Research, National Center for Advancing Translational Sciences
Awards: G1093531541, G119964413, G1339420399, Diagnostic and prognostic biomarkers for inflammatory bowel disease
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OpenAlex ID: W2143350483