Work

Burden of Diabetic Peripheral Neuropathy in Pima Indians With Type 2 Diabetes

Year: 2016

Type: article

Abstract: Diabetic peripheral neuropathy (DPN) and diabetic nephropathy (DN) share common pathological mechanisms and are favorably impacted by intensive glycemic control. American Indians have disproportionately higher rates of type 2 diabetes (T2D), younger age of diabetes onset, and earlier development of long-term complications than other ethnic groups (1). Diabetes as an underlying cause of death is 2.5–3.5 times higher among American Indians than whites, yet the DPN burden among American Indians has not been systematically evaluated. We assessed DPN prevalence in Pima Indians and evaluated the relationship between DPN and DN. A total of 79 Pima Indians with T2D (age 53 ± 11 years, diabetes duration 25 ± 6 years, 73% female, and mean HbA1c 9.5 ± 1.9% [80 ± 7 mmol/mol]) from the Gila River community were enrolled. DPN status was ascertained using the Michigan Neuropathy Screening Instrument (MNSI) …

Source: Diabetes Care

DOI: 10.2337/dc16-0082

Authors: Mamta Jaiswal, Gudeta D. Fufaa, Catherine L. Martin, Rodica Pop-Busui, Robert G. Nelson, Eva L. Feldman

Institutions: University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases

Language: English

Topic: Diabetic Foot Ulcer Assessment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Novo Nordisk Fonden, National Institute of Diabetes and Digestive and Kidney Diseases