Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome
Year: 2015
Type: article
Abstract: To the editor:
Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders characterized by (1) persistent peripheral eosinophilia, (2) target organ pathology mediated by infiltrating eosinophils, and (3) the absence of known infectious or allergic causes of hypereosinophilia.[1][1],[2][
Source: Blood
Authors: Sarah Walker, Chen Wang, Trent Walradt, Bok Sil Hong, Justin R. Tanner, Jonathan L. Levinsohn, Gerald Goh, Antonio Subtil, Stuart R. Lessin, Warren R. Heymann, Eric C. Vonderheid, Brett A. King, Richard P. Lifton, Jaehyuk Choi
Institutions: Dana-Farber Cancer Institute, Yale University, Northwestern University, University College London, Fox Chase Cancer Center, University of Pennsylvania, Cooper Medical School of Rowan University, Johns Hopkins University, Johns Hopkins Medicine, Howard Hughes Medical Institute, VA Connecticut Healthcare System
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2293079376