Work

Optimization of visual training for full recovery from severe amblyopia in adults

Year: 2016

Type: preprint

Abstract: The severe amblyopia induced by chronic monocular deprivation is highly resistant to reversal in adulthood. Here we use a rodent model to show that recovery from deprivation amblyopia can be achieved in adults by a two-step sequence, involving enhancement of synaptic plasticity in the visual cortex by dark exposure followed immediately by visual training. The perceptual learning induced by visual training contributes to the recovery of vision and can be optimized to drive full recovery of visual acuity in severely amblyopic adults.

Source: Learning & Memory

DOI: 10.1101/lm.040295.115

Authors: Nicolette C. Eaton, Hanna Marie Sheehan, Elizabeth M. Quinlan

Institution: University of Maryland, College Park

Language: English

Topic: Visual perception and processing mechanisms

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Eye Institute