Research Article - A sequential test procedure for monitoring a singular safety and efficacy outcome
Year: 2003
Type: article
Abstract: In this note we describe a modification of the sequential probability ratio test (SPRT) developed for the purpose of “flagging” a significant increase in the mortality rate of a treatment relative to a control while ensuring that double-blinding and the Type I error for the primary test of efficacy, also based on mortality rates, is not compromised.
Source: TSpace (University of Toronto)
Author: Alan D. Hutson
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2293440927