Work

High-Fat Diet, Dysbiosis, and Gastrointestinal and Colonic Transit: Is There a Missing Link?

Year: 2016

Type: article

Abstract: In a series of elegant studies reported in this issue of Cellular and Molecular Gastroenterology and Hepatology, Anitha et al1 report that a high-fat diet results in slowing of gastrointestinal transit (by geometric center of fluorescein isothiocyanate distribution after gavage), total gastrointestinal transit (by first arrival of a blue dye in stool), and distal colonic transit (by the time taken to expel a bead through the last 2 cm of colon). This retardation of transit is associated with increased numbers of fecal Firmicutes and reduced numbers of Bacteroidetes.

Source: Cellular and Molecular Gastroenterology and Hepatology

DOI: 10.1016/j.jcmgh.2016.02.002

Author: Michael Camilleri

Institution: Mayo Clinic

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,430